Table II.

Main results of the meta-analysis.

	Patients included
Results	Dexmedtomidine	Midazolam	Standard deviation Mean Difference	P-value
SpO2	224	223	1.25 [-0.31,0.61]	0.12
MAP	175	175	−0.08 [-0.29,0.1]	0.49
RSS	95	95	0.64 [0.35,0.93]	<0.0001
Adverse events
Hypertension	4	12	–
Hypotension	11	8	–
Tachycardia	13	12	–
Hypoxia	1	11	–
Nausea	10	2	–
Other	31	69	–
Total	70	112	0.40 [0.26,0.61]	<0.0001

MAP, mean arterial pressure; RSS,. Ramsay sedation scale.