Table I.

Effects of DBT on fasting blood glucose, serum creatinine and blood urea nitrogen in rats.

		Fasting blood glucose (mmol/l)		Serum creatinine (µmol/l)		Blood urea nitrogen (mmol/l)
Group	n	Before treatment	6 weeks after treatment	Before treatment	6 weeks after treatment	Before treatment	6 weeks after treatment
Normal control	8	5.3±1.12	5.2±1.53	19.85±3.21	18.11±3.22	7.1±1.21	6.9±1.42
Vehicle	7	16.8±1.21a	17.3±1.12	61.21±4.12a	75.91±5.12	10.3±2.11a	13.23±2.34
DBT-L	8	17.3±0.98a	12.2±1.31b,c	62.31±3.52a	52.11±2.34b,c	11.8±2.13a	9.21±1.02b,c
DBT-M	9	17.1±1.11a	13.1±1.51b,c	63.11±2.32a	49.13±1.28b,c	12.4±2.29a	9.11±1.13b,c
DBT-H	9	16.9±1.02a	13.4±1.22b,c	64.10±3.13a	46.32±4.19b,c	13.9±2.01a	8.32±0.12b,c
Gliclazide	9	17.2±0.92a	10.3±0.42b,c	63.89±4.11a	43.12±4.43b,c	13.4±2.32a	7.12±2.11b,c

Three rats in the vehicle group and one in the DBT-L group died during the experiment and were not included in the analysis. Data are expressed as the mean ± standard deviation. Student's t-test and one-way analysis of variance were used to analyze the differences between the two groups and among the six groups, respectively.

^aP<0.05 vs. normal control group

^bP<0.05 vs. vehicle group

^cP<0.05 vs. before treatment. DBT, Danggui Buxue Tang; DBT-L, low concentration (0.5 kg/l) DBT; DBT-M, medium concentration (1.0 kg/l) DBT; DBT-H, high concentration (2.0 kg/l) DBT.