Figure 4. EMILIN1 cleavage and neutrophil infiltration in human acquired lymphoedema.
(A) Western blotting analysis of EMILIN1 expression and cleavage in human acquired lymphoedema samples. Black arrows and red arrow indicate the most representative bands of cleaved EMILIN1 and undigested EMILIN1, respectively. (B) Paraffin-embedded sections of vulvar lymphoedema samples obtained from two patients (a and b, patient no. 1; c, patient no. 2) stained with H&E. Arrows indicate neutrophils (a′, b′, c′) and asterisks enlarged lymphatic vessels (a, b, c); a′, b′ and c′ correspond to the boxed areas in a, b and c, respectively. Scale bars=20 μm (a′, b′, c′); 50 μm (a, b, c).
