Table 3.
Colorectal cancer -specific and overall survival by age group
| Age group
|
p-within age strata | ||||||
|---|---|---|---|---|---|---|---|
| Survival Characteristic | Model | <60 years (n=224) |
60–74 years (n=756) |
75+ years (n=300) |
|||
|
| |||||||
| CRC-specific survival | 5yr | Event, N (%) | 50 (22%) | 175 (23%) | 72 (24%) | ||
|
| |||||||
| Unadjusted, HR (95% CI) | 1 (Referent) | 1.05 (0.76 to 1.43) | 1.14 (0.79 to 1.63) | 0.57 | |||
| Adjusted, HR (95% CI) | 1 (Referent) | 1.46 (1.03 to 2.09) | 2.13 (1.39 to 3.27) | 0.003 | |||
|
| |||||||
| 10yr | Event, N (%) | 60 (27%) | 207 (27%) | 81 (27%) | |||
|
| |||||||
| Unadjusted, HR (95% CI) | 1 (Referent) | 1.06 (0.80 to 1.42) | 1.15 (0.82 to 1.60) | 0.38 | |||
| Adjusted, HR (95% CI) | 1 (Referent) | 1.45 (1.06 to 1.99) | 2.15 (1.46 to 3.17) | 0.0002 | |||
|
| |||||||
| Overall survival | 5yr | Event, N (%) | 52 (23%) | 214 (28%) | 106 (35%) | ||
|
| |||||||
| Unadjusted, HR (95% CI) | 1 (Referent) | 1.24 (0.91 to 1.67) | 1.63 (1.17 to 2.27) | 0.002 | |||
| Adjusted, HR (95% CI) | 1 (Referent) | 1.67 (1.19 to 2.34) | 2.68 (1.81 to 3.96) | <.0001 | |||
|
| |||||||
| 10yr | Event, N (%) | 63 (28%) | 304 (40%) | 152 (51%) | |||
|
| |||||||
| Unadjusted, HR (95% CI) | 1 (Referent) | 1.56 (1.19 to 2.05) | 2.32 (1.73 to 3.12) | <.0001 | |||
| Adjusted, HR (95% CI) | 1 (Referent) | 1.91 (1.42 to 2.57) | 3.20 (2.29 to 4.49) | <.0001 | |||
Abbreviations: HR, hazard ratio; CI, confidence interval