Table II.
Association between the expression levels of miR-196b and the clinicopathological data of patients with oral squamous cell carcinoma.
| miR-196b (n=69) | ||||
|---|---|---|---|---|
| No. of patients (%) | ||||
| Variable | Low (n=35) | High (n=34) | χ2 | P-valuea |
| Gender | 0.633 | 0.477b | ||
| Female | 3 (37.5) | 5 (62.5) | ||
| Male | 32 (52.5) | 29 (47.5) | ||
| Age, years | 4.503 | 0.034 | ||
| ≤50 | 13 (72.2) | 5 (27.8) | ||
| >50 | 22 (43.1) | 29 (56.9) | ||
| Cancer location | 2.280 | 0.320 | ||
| Buccal | 14 (53.8) | 12 (46.2) | ||
| Tongue | 8 (66.7) | 4 (33.3) | ||
| Other oral mucosal sites | 13 (41.9) | 18 (58.1) | ||
| Cell differentiation | 2.880 | 0.090 | ||
| Well | 3 (27.3) | 8 (72.7) | ||
| Moderate, poor | 32 (55.2) | 26 (44.8) | ||
| AJCC pathological stage | 0.729 | 0.393 | ||
| I, II | 18 (56.3) | 14 (43.8) | ||
| III, IV | 17 (45.9) | 20 (54.1) | ||
| Tumor classification | 0.354 | 0.552 | ||
| T1, T2 | 20 (54.1) | 17 (45.9) | ||
| T3, T4 | 15 (46.9) | 17 (53.1) | ||
| Node classification | 0.969 | 0.325 | ||
| N0 | 23 (46.9) | 26 (53.1) | ||
| N1, N2 | 12 (60.0) | 8 (40.0) | ||
a
P-value was estimated by χ2 test.
b
P-value was estimated by Fisher's exact test. miR, microRNA; AJCC, American Joint Committee on Cancer.