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LPS-induced ALI was dependent on T cells. The number of total cells (A) and cytokine concentration (B) in the BAL fluid from WT, Rag2−/−, or CD3ε−/− mice 24h after LPS instillation. n = 3 per group. *P < 0.05. Values represent the mean ± SD. (C) The number of CD4+T cells and CD4+CD44highCD62Llow memory or effector T cells in the lung after LPS challenge. n = 4 for each point.
