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Mup-knockout mouse model enables analyzing non-MUP urinary proteins with enhanced sensitivity (A) Coomassie Brilliant Blue staining of an SDS-PAGE showing the absence of MUPs in Mup−/− mice and similar patterns of non-MUP proteins between WT and Mup−/− mice. (B) The sensitivity of ELISA toward UMOD was increased in Mup−/− mice. (C) The sensitivity of ELISA toward MAU was increased in Mup−/− mice. *P<0.05.
