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Gal-1 regulates CAF-CM-augmented MDA-MB-231 cell migration and invasion NFs and CAFs were transfected with Gal-1 cDNA and Gal-1 siRNA, respectively. Cell migration (A) and invasion (B) were measured using a transwell culture system. The CM was collected as a chemoattractant. All data were expressed as mean ± SD of three experiments. **P< 0.01 vs. NF/Con-CM; ##P< 0.01 vs. CAF/Con-CM. Con, controls; OE, overexpressions; KD, knockdowns.
