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Assessment of cyclin B1, P21, PCNA, and Ki67 mRNA expression in HCT-8 cells treated with different concentrations of abrin P2 Relative gene expressions of cyclin B1, P21, PCNA, and Ki67 in abrin P2-treated samples compared with that in untreated control samples were determined by qRT-PCR and normalized to β-actin mRNA expression. The data are presented as the mean ± SD from nine independent experiments. *P < 0.05, **P < 0.01, and ***P < 0.001 vs. control.
