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Z-VAD-FMK partially abrogated abrin P2-induced apoptosis in HCT-8 cells After the treatment of HCT-8 cells with 50 μM Z-VAD-FMK for 1 h before abrin P2 treatment, the apoptotic rates were reduced significantly compared with those in cells treated with abrin P2 only. The data are presented as the mean ± SD from three independent experiments. ***P < 0.001 vs. control; ###P < 0.001 vs. 1 × 10−2 μg/ml abrin P2; and ΔΔΔP < 0.001 vs. 1 × 10−1 μg/ml abrin P2.
