Table 2.
Characteristic | Unadjusted HR (95% CI) | Adjusted* HR (95% CI) |
---|---|---|
MRCI cont. | 1.51 (1.42–1.60) | 1.22 (1.14–1.34) |
Age | 1.06 (1.06–1.07) | 1.06 (1.05–1.07) |
Sex female | 1.04 (0.92–1.18) | 0.75 (0.65–0.88) |
Education† | ||
High school | 0.64 (0.54–0.74) | 0.84 (0.71–0.98) |
University | 0.42 (0.35–0.50) | 0.79 (0.65–0.97) |
Living place at home | 0.55 (0.45–0.66) | 1.49 (1.07–2.06) |
Modified CCI | 1.38 (1.31–1.45) | 1.09 (1.03–1.17) |
Katz ADLs | 0.88 (0.84–0.93) | 1.26 (1.06–1.45) |
MMSE | 0.64 (0.55–0.74) | 0.99 (0.97–1.01) |
Unplanned hospitalization previous year | 1.45 (1.33–1.58) | 1.24 (1.14–1.35) |
Self-reported pain | 1.26 (1.11–1.43) | 1.15 (0.99–1.32) |
Dexterity (can you open jars with lids?)‡ | ||
Yes without trouble | 0.36 (0.29–0.46) | 0.87 (0.65–1.15) |
Yes with aid | 0.54 (0.43–0.68) | 0.84 (0.63–1.11) |
Receives help sorting medication | 3.07 (2.63–2.59) | 1.55 (1.21–1.97) |
Number of medications | 1.13 (1.11–1.15) | 1.07 (1.04–1.09) |
Age | 1.06 (1.06–1.07) | 1.06 (1.05–1.07) |
Sex female | 1.04 (0.92–1.18) | 0.75 (0.64–0.87) |
Education† | ||
High school | 0.64 (0.54–0.74) | 0.84 (0.71–0.98) |
University | 0.42 (0.35–0.50) | 0.79 (0.65–0.96) |
Living place at home | 0.55 (0.45–0.66) | 1.48 (1.07–2.04) |
Modified CCI | 1.38 (1.31–1.45) | 1.09 (1.02–1.16) |
Katz ADLs | 0.88 (0.84–0.93) | 1.26 (1.09–1.45) |
MMSE | 0.64 (0.55–0.74) | 0.99 (0.97–1.01) |
Unplanned hospitalization previous year | 1.45 (1.33–1.58) | 1.24 (1.15–1.35) |
Self-reported pain | 1.26 (1.11–1.43) | 1.14 (0.99–1.31) |
Dexterity (can you open jars with lids?)‡ | ||
Yes without trouble | 0.36 (0.29–0.46) | 0.86 (0.65–1.14) |
Yes with aid | 0.54 (0.43–0.68) | 0.83 (0.63–1.10) |
Receives help to sort medication | 3.07 (2.63–2.59) | 1.54 (1.21–1.96) |
Notes: ADL = activities of daily living; CCI = Charlson’s Comorbidity Index; cont. = continuous; HR = hazard ratio; MMSE = Mini-Mental State Examination; MRCI = Medication Regimen Complexity Index (tenths, MRCI continuous divided by 10).
*Adjusted for age, sex, education, living place, modified CCI, ADLs, MMSE, unplanned admission in the previous year, self-reported pain, dexterity, receives help to sort medication.
Reference categories: †education = elementary, ‡dexterity = cannot open jars with lids.