Table 4.
Effect of Cognition Phenotype on Association of Mobility Phenotype With Mortality Among 1,495 SOF Women
| Relative Hazard (95% CI) | |||||
|---|---|---|---|---|---|
| Phenotype* | Mortality Rate Per 100 Person-Years (95% CI)† | Base Model‡ | Base Model‡ + Cognition | Multivariable Model§ | Multivariable Model§ + Cognition |
| Good mobility (SPPB 10–12) | 6.6 (5.3–7.8) | 1.00 (referent) | 1.00 (referent) | 1.00 (referent) | 1.00 (referent) |
| Intermediate mobility (SPPB 4–9) | 10.1 (9.1–11.0) | 1.62 (1.32–1.98) | 1.54 (1.25–1.88) | 1.34 (1.08–1.66) | 1.26 (1.02–1.57) |
| Poor mobility (SPPB 0–3) | 17.1 (14.7–19.5) | 2.86 (2.28–3.60) | 2.39 (1.89–3.03) | 1.84 (1.40–2.42) | 1.64 (1.24–2.16) |
Notes: SOF = Study of Osteoporotic Fractures; SPPB = Short Physical Performance Battery.
*Among the cohort, there were 384 women with good mobility, 799 women with intermediate mobility, and 312 women with poor mobility.
†Adjusted for age.
‡Adjusted for age and site.
§Adjusted for age, site, race, education, health status, hospitalization in the prior year, smoking status, comorbidity score, walking for exercise, ADL impairment, depressive symptoms, and body mass index.