Skip to main content
. 2016 May 27;473(11):1537–1552. doi: 10.1042/BCJ20160024

Figure 1. Bioinformatic analysis of the Mlt1p transporter of C. albicans.

Figure 1

(A) Pictorial representation of the putative topology of Mlt1p as predicted by TOPCONS software showing typical domain arrangement of MRPs including a regulatory domain (R-domain) in TMH 12. NTE, N-terminal extension. (B) Phylogenetic analysis of C. albicans Mlt1p with yeast ABCC/MRP transporters of known functions. The analysis shows that the Mlt1p transporter is closest to the Bpt1 transporter of S. cerevisiae. The phylogenetic tree was generated using MEGA 6 software. Values at nodes represent bootstrap values signifying confidence levels. (C) BLASTp analysis of Mlt1p and S. cerevisiae vacuolar MRP transporters (ScYbt1, ScBpt1 and ScYcf1) of known functions.