Table 4. Association of LEPR K109R Genotypes With Clinical Pathological Parameters in NAFLD Patients With and Without Coronary Atherosclerosis^a.

Clinical Characteristics	NAFLD+ Coronary Atherosclerosis+			NAFLD+ Coronary Atherosclerosis-
	AA+GA, (n = 148)	GG, (n = 201)	P Value	AA+GA, (n = 50)	GG, (n = 155)	P Value
Gender			0.650			0.962
Male	70	100		24	75
Female	78	101		26	80
Age, y	45.28 ± 11.59	47.00 ± 12.28	0.184	48.88 ± 10.32	46.04 ± 11.65	0.105
BMI, kg/m 2	24.67 ± 1.59	24.07 ± 1.69	0.001	24.34 ± 1.62	23.98 ± 1.65	0.176
ALT, U/L	24.72 ± 11.73	22.80 ± 9.98	0.096	25.94 ± 13.30	22.52 ± 8.47	0.092
AST, U/L	22.22 ± 6.93	20.79 ± 5.50	0.039	23.60 ± 9.01	20.86 ± 6.03	0.049
FPG, mmol/L	5.31 ± 0.84	5.02 ± 0.67	0.001	5.39 ± 0.92	5.18 ± 0.71	0.094
TG, mmol/L	2.06 ± 2.12	1.69 ± 1.18	0.039	2.00 ± 2.13	1.61 ± 1.13	0.101
TC, mmol/L	4.96 ± 1.02	4.75 ± 0.96	0.051	4.92 ± 0.87	4.64 ± 1.01	0.084
HDL, mmol/L	1.34 ± 0.71	1.40 ± 0.63	0.416	1.22 ± 0.31	1.35 ± 0.49	0.068
LDL, mmol/L	3.55 ± 0.95	3.47 ± 0.98	0.456	3.32 ± 1.08	3.30 ± 0.88	0.873

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; FPG, fasting blood glucose; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NAFLD, non-alcoholic fatty liver disease patients; P1, NAFLD group vs. control group; P2, coronary atherosclerosis group vs. control group; P3, NAFLD group vs. coronary atherosclerosis group; TG, triglyceride; TC, total cholesterol.

^aValues are expressed as mean±SD.