Table 1.
Gene Onthology analysis of Sus scrofa proteins detected in exosomal enriched fractions
| Ref list. 21483 | Exp. list (91) | Expected | Over/under | Fold enrichment | P value | |
|---|---|---|---|---|---|---|
| PANTHER GO-slim biological process | ||||||
| Lipid transport | 305 | 10 | 1.29 | + | >5 | 1.67E−04 |
| Response to external stimulus | 347 | 10 | 1.47 | + | >5 | 5.24E−04 |
| Proteolysis | 690 | 12 | 2.92 | + | 4.11 | 7.98E−03 |
| Response to stress | 659 | 11 | 2.79 | + | 3.94 | 2.48E−02 |
| Immune system process | 1399 | 17 | 5.93 | + | 2.87 | 1.65E−02 |
| Localization | 2610 | 28 | 11.06 | + | 2.53 | 4.69E−04 |
| Transport | 2484 | 26 | 10.52 | + | 2.47 | 1.93E−03 |
| Response to stimulus | 2364 | 23 | 10.01 | + | 2.3 | 2.31E−02 |
| Unclassified | 9376 | 24 | 39.72 | − | 0.6 | 0.00E+00 |
| PANTHER GO-slim molecular function | ||||||
| Lipid transporter activity | 106 | 8 | 0.45 | + | >5 | 3.51E−06 |
| Peptidase inhibitor activity | 227 | 10 | 0.96 | + | >5 | 8.65E−06 |
| Serine-type peptidase activity | 293 | 11 | 1.24 | + | >5 | 8.91E−06 |
| Enzyme inhibitor activity | 337 | 10 | 1.43 | + | >5 | 3.08E−04 |
| Peptidase activity | 605 | 16 | 2.56 | + | >5 | 9.26E−07 |
| Receptor binding | 947 | 18 | 4.01 | + | 4.49 | 1.42E−05 |
| Hydrolase activity | 2181 | 23 | 9.24 | + | 2.49 | 5.06E−03 |
| Protein binding | 2729 | 28 | 11.56 | + | 2.42 | 8.53E−04 |
| Unclassified | 10 794 | 35 | 45.72 | − | 0.77 | 0.00E+00 |
| PANTHER GO-slim cellular component | ||||||
| Extracellular space | 6 | 3 | 0.03 | + | >5 | 1.22E−04 |
| Extracellular region | 624 | 18 | 2.64 | + | >5 | 6.31E−09 |
| Unclassified | 17 295 | 62 | 73.26 | − | 0.85 | 0.00E+00 |