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. 2016 Jun 1;6:37. doi: 10.1186/s13578-016-0085-7

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© Han et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Paeoniflorin (PF) increases the phosphorylation of CREB (pCREB). The level of pCREB was significantly higher in the PF-WTDM group than in the other groups. a A representative image of the levels of pCREB, CREB and GAPDH. b Quantification by the ratio of pCREB to GAPDH (n = 6/group). c Quantification by the ratio of pCREB to CREB. *P < 0.05, PF-WTDM-H vs. WTDM, TRPV1^−/−DM, PF-TRPV1^−/−DM, PF-WTDM-KN-93 and PF-TRPV1^−/−DM-KN-93