Skip to main content
. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: JAMA Dermatol. 2016 Mar 1;152(3):268–275. doi: 10.1001/jamadermatol.2015.2938

Table 1.

Phenotypic and UV Radiation Behavior Among Cases (by Age Range at Diagnosis) and Controls (Reference Age Range)

Age at Diagnosis or Reference Age Range
< 30 y
No. = 144
30 – 39 y
No. = 391
40 – 49 y
No. = 800
Characteristic Cases
No. = 76
Controls
No. = 68
Cases
No. = 198
Controls
No. = 193
Cases
No. = 407
Controls
No. = 393
Women
No. 63 61 140 135 262 250
Phenotype risk score, mean 3.0 2.9 3.1 2.7b 3.1 2.8c
Blue eyes, % 46.0 41.0 42.9 33.3a 41.2 36.0
Fair or very fair skin, % 85.7 77.1 83.6 81.5 87.4 80.0
Freckles pattern (mean, score 1 – 4) 1.9 1.8 1.6 1.7 2.0 1.8a
Mole pattern (mean, score 1 – 4) 2.4 1.9d 2.3 1.8d 2.1 1.7d
Melanoma family history, % 24.6 28.8 20.1 15.4 18.5 19.6
Routine sun, median, × 100 h 11.0 11.6 15.3 14.9 20.4 21.0
Outdoor activity sun, median, × 100 h 7.7 8.2 11.3 11.1 15.1 15.4
Sunburns, median, No. 9.0 6.5 7.0 6.0 10.0 6.0d
Ever tanned indoors, % 96.8 83.6a 94.3 79.3c 78.6 62.0d
  Age of initiation, median, y 16.0 16.0 16.0 17.0 24.5 25.0
  Sessions, median, No. 110.0 95.0 130.0 73.0a 49.5 28.0b
Tumors located on trunk, % 33.3 NA 35.0 NA 24.4 NA
Men
No. 13 7 58 58 145 143
Phenotype risk score, mean 3.4 2.4 2.8 2.4a 2.9 2.7a
Blue eyes, % 30.8 42.9 39.7 31.0 46.9 41.3
Fair or very fair skin, % 92.3 57.2 89.7 70.7a 90.3 83.9
Freckles pattern (mean, score 1 – 4) 2.2 1.4 1.8 1.5a 1.9 1.6b
Mole pattern (mean, score 1 –4) 2.1 2.0 2.2 1.8c 2.1 1.7d
Melanoma family history, % 7.7 16.7 17.2 29.3 17.6 19.6
Routine sun, median, × 100 h 13.0 13.3 21.8 22.8 26.8 30.0
Outdoor activity sun, median, × 100 h 10.1 9.4 13.1 14.0 15.6 19.8
Sunburns, median, No. 40.0 6.0a 12.0 9.5 12.0 9.0
Ever tanned indoors, % 46.2 57.1 51.7 44.8 47.5 37.1
  Age of initiation, median, y 16.5 16.0 19.5 20.5 25.0 30.0
  Sessions, median, No. 7.0 70.5 22.0 12.5 20.0 24.5
Tumors located on trunk, % 46.2 NA 41.4 NA 49.0 NA

Abbreviation: NA, not applicable.

Statistical significance for difference between cases and controls:

a

p-value < 0.05;

b

p-value < 0.01;

c

p-value < 0.001;

d

p-value ≤ 0.0001.