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. 2016 May 26;9:3137–3146. doi: 10.2147/OTT.S102338

Figure 5.

Figure 5

YAP1 knockdown suppressed the growth of esophageal tumors in vivo.

Notes: (A) In the YAP1-knockdown group (sh-YAP1), the tumor volume was significantly decreased compared to that in the control group. (B) After 4 weeks, the tumor weight was significantly decreased in the YAP1-knockdown group compared to that in the control group. (C) YAP1 knockdown decreased expression of Ki67, Bax, MMP-2, and MMP-9 and increased expression of Bcl-2 compared to controls. *P<0.05 and **P<0.01.

Abbreviation: sh-YAP1, short-hairpin RNA expression vector targeting YAP1.