Table 1.
Correlation between miR-200b expression and clinicopathologic features of patients with osteosarcoma
| Clinicopathologic features | Cases (n) | 200b expression
|
P-value | |
|---|---|---|---|---|
| High, n (%) | Low, n (%) | |||
| Sex | ||||
| Male | 15 | 6 (40.0) | 9 (60.0) | NS |
| Female | 17 | 7 (41.2) | 10 (58.8) | |
| Age (years) | ||||
| ≤28 | 19 | 8 (42.1) | 11 (57.9) | NS |
| <28 | 13 | 5 (38.5) | 8 (61.5) | |
| Tumor size (diameter) | ||||
| ≤5 cm | 14 | 6 (42.8) | 8 (59.6) | NS |
| <5 cm | 18 | 7 (38.9) | 11 (61.1) | |
| WHO grade | ||||
| I and II | 12 | 9 (75.0) | 3 (25.0) | 0.0001 |
| III and IV | 20 | 4 (20.0) | 16 (80.0) | |
| Distant metastasis | ||||
| Positive | 13 | 2 (15.4) | 11 (84.6) | 0.0001 |
| Negative | 19 | 11 (57.9) | 8 (42.1) | |
Abbreviations: miR, microRNA; NS, not significant; WHO, World Health Organization.