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. 2016 May 24;9:3077–3084. doi: 10.2147/OTT.S102658

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© 2016 Lu et al. This work is published and licensed by Dove Medical Press Limited

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ANRIL expression in NSCLC and its clinical significance.

Notes: (A) Difference in expression levels of ANRIL expression levels between NSCLC tissues and matched normal tissues. The expression of ANRIL was normalized to β-actin. The statistical differences between samples were analyzed with Wilcoxon signed-rank test (n=56, P<0.01). (B) Relationship between ANRIL expression and primary tumor growth (P<0.01). (C) Relationship between ANRIL expression and TNM stage (P<0.01). (D) qRT-PCR analysis of ANRIL expression levels in NSCLC cell lines (SK-MES-1, SPC-A1, NCI-H1975, and A549) compared with the normal bronchial epithelial cell line (16HBE). **P<0.01.

Abbreviations: NSCLC, non-small-cell lung cancer; qRT-PCR, quantitative real-time polymerase chain reaction; TNM, tumor–node–metastasis.