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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: J Immunol. 2016 Apr 25;196(11):4671–4680. doi: 10.4049/jimmunol.1600040

Figure 6. C5a directly enhances TRAP-mediated PGA formation and CD11b expression.

Figure 6

Lepirudin anticoagulated whole blood was incubated without or with TRAP (10μM) +/− C5a (210nM) or C5a + PMX53 (16.7μM). Results are representative of 5 independent experiments in which PGA formation (A) and CD11b (B) expression on granulocytes were determined in the same experiment, as described in Materials and Methods. Results are shown as mean and SD of duplicate observations. The data was analyzed by one-way ANOVA with Tukey’s multiple comparison test. p<0.01 (**) and p<0.001 (***).