FIGURE 2.
GSK-3β inhibition interferes with T cell activation. Purified peripheral T cells were stimulated with anti-CD3 and anti-CD28 mAbs in the presence of increasing concentrations of the GSK-3β inhibitor. A and B, Secretion of IFN-γ (A) and IL-2 (B) was measured by ELISA 16 h poststimulation. C, [3H]Thymidine incorporation was measured 48 h poststimulation. A representative of two independent experiments is shown. **p< 0.01.