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. 2016 May 11;1(3):e00036-16. doi: 10.1128/mSphere.00036-16

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Copyright © 2016 Bowden et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Large-scale genome rearrangements within a subset of California (H561 and H563, blue) and Vermont (I496 and I707, red) epidemic isolates compared to vaccine strains E476 and C393 as visualized by whole-genome restriction mapping and alignment with MapSolver (A) and genome sequence alignment with progressiveMauve (B). Connecting lines indicate either conserved restriction fragments (A) or homologous sequence blocks (B). Sequence maps begin at the replication origin, and the approximate replication terminus is indicated with an arrow.