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a) Stereospecific conversion of (3S,4R)-tetrahydrodaidzein (THD) to (S)-equol and b) the proposed mechanistic pathway of (3S,4R)-THD to (S)-equol catalyzed by tetrahydrodaidzein reductase (THDR) according to Kim et al. 2010 (Kim, Marsh, Kim et al., 2010).
