Table 1.
Factor levels and type of second-derivative curve in the activated partial thromboplastin time assay
| Calculated level of factor (%) | Factor | |||||||||
| V | VIII | IX | XI | XII | ||||||
| Measured level of factor (%) | Type of curve | Measured level of factor (%) | Type of curve | Measured level of factor (%) | Type of curve | Measured level of factor (%) | Type of curve | Measured level of factor (%) | Type of curve | |
| 0 | 0.6 | ABN-B | 0.3 | ABN-B | 0.4 | ABN-B | 0.5 | ABN-B | 0.4 | ABN-S |
| 2 | 2.5 | ABN-S | 3.6 | ABN-S | 5.5 | ABN-S | 4.1 | ABN-S | 2.3 | N |
| 4 | 3.9 | ABN-S | 5.8 | ABN-S | 6.7 | ABN-S | 5.8 | N | 3.8 | N |
| 10 | 10.2 | N | 11.7 | ABN-S | 15.1 | ABN-S | 10.8 | N | 11.4 | N |
| 20 | 17.7 | N | 17.9 | N | 28.5 | N | 20.9 | N | 22.7 | N |
| 50 | 46.3 | N | 48.3 | N | 64.3 | N | 46.6 | N | 52.8 | N |
| 80 | 72.3 | N | 70.3 | N | 90.8 | N | 69.0 | N | 72.4 | N |
| 100 | 92.8 | N | 80.7 | N | 115.7 | N | 85.0 | N | 86.4 | N |
Factor activity was determined in a standard one-stage assay using activated partial thromboplastin time (APTT) SynthASil. APTT assay for waveform analysis was performed using APTT-SP. ‘Type of curve’ indicates the status of the second-derivative curve in the APTT assay. ABN-B, abnormal biphasic-type; ABN-S, abnormal shoulder-type; N, normal.