Table 3.
Two observers’ mean sensitivity, specificity, and diagnostic accuracy for the diagnosis of MND using qualitative analysis. A test was considered positive if there was mild/marked hypointensity on T2 or T2*, mild or marked hyperintensity on T2 FLAIR, or moderately/markedly more hyperintensity on QSM. The last row shows the weighted kappa between both observers for each sequence.
| T2 | T2* | T2 FLAIR | QSM | |
|---|---|---|---|---|
| Sensitivity | 53% | 69% | 34% | 88% |
| Specificity | 96% | 54% | 100% | 80% |
| Accuracy | 78% | 60% | 73% | 83% |
| Kappa | 0.66 | 0.80 | 0.89 | 0.89 |