Table 1.
Baseline Characteristics of Study Participants According to Incident Atrial Fibrillation: ARIC, MESA, and RS
| ARIC | MESA | RS | |||||||
|---|---|---|---|---|---|---|---|---|---|
| All (n=13 907) | No AF (n=12 276) | AF (n=1631) | All (n=6640) | No AF (n=6330) | AF (n=310) | All (n=5220) | No AF (n=4921) | AF (n=299) | |
| Age, y (SD) | 57.0 (5.7) | 56.7 (5.7) | 59.8 (5.4) | 62.0 (10.2) | 61.6 (10.1) | 70.4 (8.1) | 69.0 (7.8) | 68.8 (7.8) | 73.2 (7.3) |
| Women | 7714 (55.5) | 6907 (56.8) | 744 (45.6) | 3504 (52.8) | 3385 (53.5) | 119 (38.4) | 2956 (56.6) | 2803 (57.0) | 153 (51.2) |
| Nonwhite race | 3311 (23.8) | 3037 (24.7) | 274 (16.8) | 2614 (39.4) | 2526 (39.9) | 88 (28.4) | NA | NA | NA |
| Height, cm (SD) | 168.5 (9.3) | 168.2 (9.3) | 170.3 (9.5) | 166.4 (10.0) | 166.3 (10.0) | 168.6 (10.4) | 167.3 (9.3) | 167.3 (9.2) | 168.2 (10.3) |
| Weight, kg (SD) | 79.3 (16.7) | 78.6 (16.4) | 84.6 (17.7) | 78.6 (17.3) | 78.5 (17.3) | 81.7 (17.5) | 75.7 (13.0) | 75.5 (12.9) | 78.0 (13.3) |
| Current smoker | 3113 (22.4) | 2702 (22.0) | 411 (25.2) | 861 (13.0) | 825 (13.0) | 36 (11.6) | 1025 (19.6) | 979 (19.9) | 46 (15.4) |
| Diabetes | 2049 (14.7) | 1692 (13.8) | 357 (21.9) | 836 (12.6) | 790 (12.5) | 46 (14.8) | 664 (12.7) | 616 (12.5) | 48 (16.1) |
| HTN medication use | 4528 (32.6) | 3720 (30.3) | 808 (49.5) | 2449 (36.9) | 2273 (35.9) | 176 (56.8) | 1760 (33.7) | 1606 (32.6) | 154 (51.5) |
| Systolic BP, mm Hg (SD) | 121.4 (18.7) | 120.7 (18.4) | 126.8 (20.2) | 126.5 (21.5) | 126.0 (21.3) | 135.6 (22.0) | 143.4 (21.1) | 143.1 (20.9) | 149.5 (24.2) |
| Diastolic BP, mm Hg (SD) | 72.0 (10.2) | 72.0 (10.1) | 72.2 (10.9) | 71.9 (10.3) | 71.9 (10.3) | 72.0 (10.3) | 76.9 (11.1) | 76.9 (11.0) | 76.6 (11.7) |
| History of MI | 140 (1.0) | 113 (0.9) | 27 (1.7) | NA | NA | NA | 319 (6.1) | 289 (5.9) | 30 (10.0) |
| History of heart failure | 69 (0.5) | 52 (0.4) | 17 (1.0) | NA | NA | NA | 125 (2.4) | 112 (2.3) | 13 (4.3) |
| Carotid plaquea | 4748 (34.4) | 4001 (32.9) | 747 (46.2) | 846 (12.8) | 760 (12.1) | 86 (27.9) | 2595 (52.6) | 2413 (51.9) | 182 (64.3) |
| cIMT, mm (SD)b | 0.75 (0.20) | 0.74 (0.19) | 0.82 (0.24) | 0.87 (0.19) | 0.86 (0.19) | 0.99 (0.24) | 1.04 (0.19) | 1.04 (0.19) | 1.11 (0.19) |
| DC, 10−3/kPa (SD)c | 16.8 (6.8) | 17.0 (6.9) | 15.1 (6.1) | 18.8 (8.1) | 19.0 (8.2) | 15.4 (7.0) | 11.5 (4.7) | 11.6 (4.7) | 10.2 (4.1) |
| PWV, m/s (SD)d | NA | NA | NA | NA | NA | NA | 13.1 (3.1) | 13.1 (3.1) | 14.4 (3.7) |
Data are presented as No. (%) of participants unless otherwise stated. There were 13 907, 6640, and 5220 participants who had data on at least one arterial measurement in ARIC, MESA, and RS, respectively. AF indicates atrial fibrillation; ARIC, Atherosclerosis Risk in Communities; BP, blood pressure; cIMT, carotid intima‐media thickness; DC, distensibility coefficient; HTN, hypertension; MESA, Multi‐Ethnic Study of Atherosclerosis; MI, myocardial infarction; NA, not applicable; PWV, pulse wave velocity; RS, Rotterdam Study.
No. of participants in ARIC, 13 796; MESA, 6595; RS, 4929.
No. of participants in ARIC, 13 595; MESA, 6605; RS, 4839.
No. of participants in ARIC, 10 300; MESA, 6417; RS, 4015.
No. of participants in RS, 4639.