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. 2016 May 3;5(5):e003146. doi: 10.1161/JAHA.115.003146

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© 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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A, Adjusted curves of event‐free survival according to AVA categories with patients with mild to moderate AS as the referent group. B, Cumulative hazard of death according to AVA ≤0.6, 0.6–0.8, and 0.8–1 cm², with patients with mild to moderate AS as the referent group. Curves are adjusted for age, sex, comorbidity index, coronary artery disease, hypertension, atrial fibrillation, and left ventricular ejection fraction. AS indicates aortic stenosis; AVA, aortic valve area; AVR, aortic valve replacement.