Table 1.
Baseline Demographic and Clinical Characteristics of the Study Patients According to Aortic Valve Area
| Overall | AVA ≤0.6 cm2 | AVA 0.6–0.8 cm2 | AVA 0.8–1.0 cm2 | P Value | |
|---|---|---|---|---|---|
| Number of patients | 199 | 39 | 80 | 80 | |
| Demographic and baseline data | |||||
| Age, y | 69±14 | 71±12 | 68±15 | 70±13 | 0.62 |
| Male | 110 (55) | 16 (41) | 46 (58) | 48 (60) | 0.13 |
| BMI, kg/m2 | 26 (23–30) | 25 (21–30) | 26 (23–31) | 27 (24–29) | 0.23 |
| SBP, mm Hg | 130 (120–150) | 130 (120–140) | 130 (120–150) | 138 (125–153) | 0.22 |
| DBP, mm Hg | 71 (69–80) | 70 (63–80) | 70 (68–80) | 74 (70–83) | 0.53 |
| Medical history and risk factors | |||||
| Diabetes mellitus | 54 (27) | 14 (36) | 18 (23) | 22 (28) | 0.30 |
| Dyslipidemia | 87 (44) | 18 (46) | 31 (39) | 38 (48) | 0.53 |
| Smoking | 57 (29) | 12 (31) | 26 (33) | 19 (24) | 0.45 |
| Hypertension | 118 (59) | 24 (62) | 42 (53) | 52 (65) | 0.27 |
| Coronary artery disease | 75 (38) | 14 (36) | 34 (43) | 27 (34) | 0.50 |
| History of atrial fibrillation | 45 (23) | 12 (31) | 15 (19) | 18 (23) | 0.30 |
| Charlson comorbidity index | 1 (1–2) | 1 (1–3) | 1 (1–2) | 1 (1–3) | 0.70 |
Statistical significance was considered for a P value of ≤0.025 according to the Bonferroni correction for 2 comparisons (AVA ≤0.6 cm2 vs 0.8–1.0 cm2 and 0.6–0.8 cm2 vs 0.8–1.0 cm2) for continuous variables expressed as median (interquartile range). AVA indicates aortic valve area; BMI, body mass index; DBP, diastolic blood pressure; SBP, systolic blood pressure.