Table 3.
Relative Risk of Events (All‐Cause Death or Aortic Valve Replacement Surgery) During Follow‐up Associated With Aortic Valve Area
| Hazard Ratio | 95% CI | P Value | |
|---|---|---|---|
| AVA categories | |||
| Unadjusted | |||
| AVA ≤0.6 cm2 | 2.19 | 1.40–3.40 | 0.001 |
| AVA >0.6 to ≤0.8 cm2 | 1.35 | 0.91–1.99 | 0.13 |
| AVA >0.8 to ≤1.0 cm2 | Referent | ||
| Adjusteda | |||
| AVA ≤0.6 cm2 | 2.22 | 1.41–3.52 | 0.001 |
| AVA >0.6 to ≤0.8 cm2 | 1.38 | 0.93–2.05 | 0.11 |
| AVA >0.8 to ≤1.0 cm2 | Referent | ||
| Per 0.1 cm2 AVA decrement | |||
| Unadjusted | 1.16 | 1.06–1.28 | 0.002 |
| Adjusteda | 1.17 | 1.06–1.29 | 0.002 |
AVA indicates aortic valve area.
a
Adjustment for age, sex, hypertension, coronary artery disease, history of atrial fibrillation, Charlson comorbidity index, and left ventricular ejection fraction.