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Skp2 and Skp2B led to breast cancer cell cycle arrest. The MCF-7 (A) and T47D (B) cells were transfected Skp2 or Skp2B vector or control vector for 48 h, and then cell cycle distribution was determined by flow cytometry analysis using PI staining. Data were represented as the average of 3 independent experiments. *P < 0.05, as compared with control vector transfected cells.
