Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Cyclin D1 is the only D-type cyclin misexpressed in teratoma-susceptible gonocytes during the mitotic:meiotic switch. (A-D) Oct4::GFP transgenic FVB, 129 and M19 gonocytes from E13.5-E15.5 gonads were isolated by FACS and expression of G1-S phase cyclins Ccnd2, Ccnd3, Ccne1, and Ccne2, respectively, was analyzed by qPCR (n = 4-23). Gene expression at all embryonic time points is plotted relative to expression in E13.5 FVB male germ cells. *, P < 0.05.
