Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Overcoming kinetic barriers such as p53, cell cycle and extracellular environment enables highly efficient transdifferentiation of human fibroblasts to induced dopaminergic (iDA) neurons by Ascl1, Nurr1, Lmx1a and miR124. This epigenetic conversion is dependent on the DNA hydroxylase Tet1.
