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The effect of E-cadherin expression alterations on tumorigenic ability of A549 cells.
| Tumorigenicity (%)* |
|||||
|---|---|---|---|---|---|
| Sublines | 1×106 | 0,5×106 | 0,25×106 | 0,125×106 | 0,05 ×106 |
| CDH1 | 100% | 100% | 50% | 0% | 0% |
| shGFP | 100% | 100% | 75% | 15% | 0% |
| shCDH1 | 100% | 100% | 100% | 50% | 10% |
Number of mice with tumors/total number of mice with injected cells.
