Table 3.
Lysophosphatidylcholine (LPC), ether-linked LPC (LPC O), lysophosphatidylethanolamine (LPE), and ether-linked LPE (LPE O) species changed to a statistically significant extent 24 h post-IR-induced AKI
| Lipid | MS/MS, m/z | Intensity Change | Fold- Change | Lipid | MS/MS, m/z | Intensity Change | Fold- Change |
|---|---|---|---|---|---|---|---|
| LPC 18:0 | 524.4_184.1 | 718.1→1325.2 | +1.85 | LPC O-22:5 | 556.4_184.1 | 110.2→ND | − |
| LPC 20:0 | 552.4_184.1 | 103.1→ND | − | LPC O-22:6 | 554.1_184.1 | 207.7→ND | − |
| LPC 20:4 | 544.4_184.1 | 58.5→ND | − | LPC O-24:1 | 592.4_184.1 | 20.3→142.4 | +7.02 |
| LPC 26:6 | 624.4_184.1 | 16.4→160.0 | +9.76 | LPC O-24:2 | 590.4_184.1 | 22.2→173.0 | +7.79 |
| LPC O-14:0 | 454.3_184.1 | 24.1→50.8 | +2.11 | LPC O-24:3 | 588.5_184.1 | 119.4→379.2 | +3.18 |
| LPC O-16:0 | 482.4_184.1 | 353.1→800.4 | +2.27 | LPC O-24:6 | 582.4_184.1 | 77.7→ND | − |
| LPC O-16:2 | 478.3_184.1 | 43.2→ND | − | LPC O-28:6 | 638.5_184.1 | ND→80.2 | + |
| LPC O-20:0 | 538.4_184.1 | 266.4→39.0 | −6.83 | LPE 16:0 | 454.3_313.3 | 30.9→190.3 | +6.16 |
| LPC O-20:3 | 532.4_184.1 | 102.7→ND | − | LPE 18:0 | 482.4_341.3 | 53.2→307.3 | +5.78 |
| LPC O-20:4 | 530.4_184.1 | 94.7→ND | − | LPE 22:0 | 538.4_198.1 | 443.9→29.7 | −14.95 |
| LPC O-22:0 | 566.4_184.1 | 104.0→ND | − | LPE 24:6 | 568.4_198.1 | 91.6→ND | − |
| LPC O-22:1 | 564.4_184.1 | 49.3→ND | − | LPE O-20:0 | 496.3_198.1 | 185.5→14.5 | −12.79 |
| LPC O-22:3 | 560.4→184.1 | 111.2→39.7 | +2.80 | LPE O-26:3 | 574.4_198.1 | 21.1→ND | − |
| LPC O-22:4 | 558.4_184.1 | 114.0→ND | − |
Reductions are highlighted in bold.