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. 2016 Feb 17;310(10):F1089–F1102. doi: 10.1152/ajprenal.00605.2015

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Fig. 11. — Presence of control and modified albumin in blood and urine after infusion. Rat albumin was infused into rats, and blood and urine samples were collected and analyzed by SDS-PAGE. Gels were imaged for fluorescence and stained for total protein using Coomassie blue stain. A: blood samples quantitated in Fig. 10C showing the more rapid vascular clearance of the modified albumins. P, preinfusion; E, early (<15 min). Note that 500 mM glucose-modified albumin had the most rapid clearance. B: 24-h urine from 8 rats was analyzed. Rats 1–4 received modified albumin and rats 5–8 received control albumin. Note the increased presence of intact albumin in rats that received albumin with decreased FcRn binding.