Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 May 9;113(21):5928–5933. doi: 10.1073/pnas.1522071113

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 5. — Sphingolipid metabolite profiles in the brain with neuronal expression of Cers2. (A–E) Free LCB levels in the brain, including dihydrosphingosine (dhSph; A), sphingosine (Sph, B), dihydrosphingosine-1-phosphate (dhS1P; C), sphingosine-1-phosphate (S1P; D), 1-deoxy-sphinganine (DeoSa; E), and 1-deoxy-sphingosine (DeoSph; F). (G) Total LCB levels, including free LCBs and LCB moieties in brain sphingolipids. (H) SPT activity of brain microsomes using 20 µM C16-CoA substrate. Four mice (n = 4) of wild type (+/+) and three mice (n = 3) of CerS1^to/to or CerS1^to/to;Tg-Cers2 were used. Values are mean ± SD. *P ≤ 0.05; **P ≤ 0.01 (one-way ANOVA, multiple comparisons).