Table S1.

Summary of brain targets of individual ipRGCs

Innervation patterns	SCN, %	IGL, %	vLGN, %	PN, %	SC, %	VMH, %	pHb, %	Total no.
Total	100	95	20	50	30	5	5	20
With SCN innervation	NA	95	20	50	30	5	5	20
With IGL innervation	100	NA	21	53	32	5	5	19
With vLGN innervation	100	100	NA	75	75	0	0	4
With PN innervation	100	100	30	NA	30	10	0	10
With SC innervation	100	100	50	50	NA	0	0	6

Shown is the quantification of innervation pattern from M1 ipRGCs to different brain regions in this study. IGL: intergeniculate leaflet; pHb: peri-Habenular region; PN: pretectal nucleus; SC: superior colliculus; SCN: suprachiasmatic nucleus, vLGN: ventral part of the lateral geniculate nucleus, VMH: ventral medial hypothalamus. NA, not applicable.