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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Obesity (Silver Spring). 2008 May 8;16(7):1708–1713. doi: 10.1038/oby.2008.262

Table 2. Significant (P < 0.05) association (measured genotype approach) of SNPs with key MS-related phenotypes.

SNP MAF (%) Location (bp) HDL-C ln Leptin FPG FSI SS T2DM BMI ln TG Total
rs1800949 29.9 −768 0.038 1
rs876507 1.1 2,330 0.042 1
rs4086314 28.8 3,407 0.027 1
rs6918013 6.4 9,386 0.032 0.0047 2
rs943004 4.4 11,544 0.046 1
rs7756163 48.2 13,331 0.048 1
rs6917903 30.7 18,284 0.010 1
rs1830971 41.3 19,021 0.0096 1
rs2021966 49.8 21,107 0.038 0.041 2
rs9372999 10.6 23,820 0.0068 1
rs7754609 7.9 25,598 0.020 1
rs997509 1.8 38,645 0.045 1
rs7769058 5.5 63,662 0.039 1
rs7769712 9.2 64,063 0.037 1
rs6928362 2.5 81,349 0.012 0.032 2
rs1974201 43.3 81,789 0.045 1
rs6929388 2.5 81,858 0.015 0.049 2
rs7754586 44.9 83,410 0.013 1
rs7754859 47.2 83,476 0.042 1
rs1931009 5.8 85,336 0.044 1
Total 7 6 4 1 2 2 1 1 24

FPG, fasting plasma glucose; FSI, fasting-specific insulin; HDL-C, high-density lipoprotein cholesterol; ln, natural log-transformed; MAF, minor allele frequency; MS, metabolic syndrome; SNP, single-nucleotide polymorphisms; SS, sum of skinfold thickness; T2DM, type 2 diabetes mellitus; TG, triglyceride.

P values <0.01 are indicated in boldface.