Table 3. Genotype class specific mean values for the traits that were associated (P < 0.01) with SNPs in ENPP1.

Trait	SNP	MAF (%)	Major/major	Major/minor	Minor/minor	Direction of change	P value
HDL-C	rs1830971	41.3	32.3 ± 1.3	34.8 ± 1.2	37.2 ± 1.7	↑	0.0096
HDL-C	rs9372999	10.6	34.7 ± 1.2	31.0 ± 1.5	27.4 ± 2.6	↓	0.0068
FPG	rs6918013	6.4	92.8 ± 1.2	97.2 ± 1.8	101.6 ± 3.4	↑	0.0047

Measured genotype additive trait mean values ± s.e. are shown for the two most significantly associated traits, FPG (mg/dl) and HDL-C (mg/dl).

FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; MAF, mean allele frequency.