Table 2.
Significance levels for SNPs previously reported to be associated with suicidal behavior or MDD in live and postmortem subjects (uncorrected p-values). All models were adjusted by age and sex.
| Y=attempted suicide/suicide death | Y=MDD | ||||||
|---|---|---|---|---|---|---|---|
| postmortem | live | live | live | ||||
| Gene | SNP | suicide death (n=121) vs non-suicide (n=88) |
suicide attempter (n=87) vs non-attempter (n=190) |
MDD attempter (n=87) vs MDD non-attempter (n=132) |
MDD (n=219) vs healthy volunteer (n=56) |
||
| p-value | p-value | risk genotype |
p-value | risk genotype |
p-value | ||
| FKBP5 | rs3800373 | 0.628 | 0.062 | 0.188 | 0.179 | ||
| rs9296158 | 0.525 | 0.038 | GG | 0.102 | 0.292 | ||
| rs3777747 | 0.533 | 0.017 | GG | 0.018 | GG | 0.749 | |
| rs4713902 | 0.799 | 0.031 | GG | 0.041 | GG | 0.535 | |
| rs9470080 | 0.602 | 0.154 | 0.240 | 0.450 | |||
| NR3C1 | rs6196 | 0.257 | 0.621 | 0.576 | 0.982 | ||
| rs33388 | 0.443 | 0.860 | 0.824 | 0.426 | |||
| rs33389 | 0.173 | 0.286 | 0.286 | 0.968 | |||
| rs10052957 | 0.153 | 0.958 | 0.911 | 0.732 | |||