Table 4.

Gene expression summary statistics for three groups of subjects (NPC=non-psychiatric controls, DNS=depressed non-suicides, DSUI=depressed suicides). Significance levels are reported for two tests comparing MDD and non-MDD subjects (DSUI+DNS vs. NPC), and suicide and non-suicide (DSUI vs. DNS+HC) subjects.

Gene	Transcript ID	Name	Biotype	Length(bp)	Protein	NPC(n=29)		DNS(n=9)		DSUI(n=21)		MDD: non-MDD	suicide: non-suicide
						M	Q	M	Q	M	Q	p-value	p-value
NR3C1	XLOC_NR3C1	Total				1.893E+01	4.072E+00	1.956E+01	7.019E+00	1.834E+01	5.372E+00	0.942	0.838
	ENST00000504572	NR3C1-010	protein coding	3389	778aa	2.821E−01	8.384E−02	2.415E−01	1.651E−01	2.189E−01	1.885E−01	0.270	0.206
	ENST00000394464	NR3C1-002	protein coding	6795	777aa	1.528E+01	4.569E+00	1.471E+01	3.583E+00	1.515E+01	5.153E+00	0.117	0.208
	ENST00000343796	NR3C1-201	protein coding	7286	777aa	2.907E−01	2.066E−01	1.653E−01	2.831E−01	2.052E−01	3.319E−01	0.215	0.751
	ENST00000394466	NR3C1-006	protein coding	3245	778aa	7.848E−01	5.700E−01	9.833E−01	6.217E−01	4.246E−01	6.456E−01	0.128	<0.001
	ENST00000231509	NR3C1-001	protein coding	3556	778aa	2.507E−04	4.405E−03	1.848E−04	5.918E−03	2.975E−03	5.456E−01	0.095	0.065
	ENST00000503201	NR3C1-007	protein coding	2594	777aa	1.298E+00	9.094E−01	6.722E−01	1.379E+00	1.321E+00	1.240E+00	0.589	0.722
	ENST00000505058	NR3C1-012	processed transcript	491	no protein	3.421E−01	1.891E−01	3.259E−01	2.901E−01	2.773E−01	2.925E−01	0.358	0.289
FKBP5	XLOC_FKBP5	Total				1.913E+00	2.097E+00	3.160E+00	2.810E+00	3.907E+00	3.576E+00	0.205	0.276
	ENST00000357266	FKBP5-001	protein coding	3772	457aa	1.589E+00	1.597E+00	2.571E+00	2.157E+00	9.831E−01	1.917E+00	0.961	0.034
	ENST00000542713	FKBP5-203	protein coding	7384	268aa	1.935E−01	4.183E−01	4.979E−01	8.417E−01	1.304E−01	2.848E−01	0.772	0.111
SKA2	XLOC_SKA2	Total				1.032E+01	1.930E+00	1.115E+01	1.481E+00	1.131E+01	4.993E+00	0.720	0.700
	ENST00000578519	SKA2-005	Nonsense mediated decay	894	61aa	1.811E+00	2.647E+00	3.207E+00	1.774E+00	3.057E+00	2.510E+00	0.014	0.087
	ENST00000437036	SKA2-002	protein coding	625	75aa	3.451E−01	9.310E−01	2.115E−01	4.825E−01	5.057E−01	5.394E−01	0.317	0.673
	ENST00000578105	SKA2-009	protein coding	689	92aa	5.313E−01	8.867E−01	3.431E−01	4.041E−01	4.545E−01	8.985E−01	0.550	0.641
	ENST00000583927	SKA2-007	processed transcript	533	no protein	1.367E+00	8.962E−01	9.805E−01	6.434E−01	1.368E+00	7.110E−01	0.889	0.267
	ENST00000581068	SKA2-008	protein coding	595	62aa	1.289E+00	8.004E−01	1.803E+00	1.155E+00	1.432E+00	1.271E+00	0.694	0.913
	ENST00000330137	SKA2-001	protein coding	2798	121aa	3.129E+00	2.832E+00	2.173E+00	2.535E+00	2.915E+00	3.281E+00	0.087	0.780
	ENST00000580541	SKA2-003	protein coding	689	46aa	5.188E−01	7.740E−01	4.666E−01	6.348E−01	3.605E−01	7.086E−01	0.510	0.447

Adjusted by age, sex and RIN score.