Table 3. Relationships of duration of heavy drinking (DHD, years) to cerebellar volume for AL men and women.

The 95% confidence interval (CI) of the slope (B) for volumes (as a proportion of estimated total intracranial volume, expressed as a percentage of the overall means) and partial r² as a function of DHD are presented for all alcoholics combined, as well as AL men and women separately. Partial r² was calculated with the formula: SS_term/(SS_term + SS_error). Age was included as a covariate for all analyses. Effects significant at p < 0.05 are in bold. *DHD by gender interaction (p < 0.05).

	Duration of Heavy Drinking (years)
	All AL		AL Men		AL Women
	N=44		N=23		N=21
Structural regions	95% CI	Partial r2	95% CI	Partial r2	95% CI	Partial r2
Total Cerebellum	[-0.6, 0.0]	0.10	[-0.5, 0.3]	0.03	[-0.7, 0.7]	0.00
White Matter	[-0.7, 0.2]	0.02	[-0.7, 0.6]	0.00	[-1.6, 0.6]	0.05
Gray Matter	[-0.7, 0.0]	0.08	[-0.6, 0.3]	0.03	[-0.7, 0.9]	0.00
Anterior Lobe*	[-1.8, -0.4]	0.18	[-2.3, -0.6]	0.37	[-1.1, 2.4]	0.03
Posterior Lobe	[-0.6, 0.2]	0.03	[-0.5, 0.5]	0.00	[-0.8, 0.9]	0.00
Vestibulocerebellum	[-1.5, -0.2]	0.15	[-1.6, 0.2]	0.11	[-2.2, 0.9]	0.05
Cerebrocerebellum	[-0.6, 0.1]	0.03	[-0.5, 0.4]	0.00	[-0.7, 1.1]	0.01
Spinocerebellum	[-0.9, -0.1]	0.13	[-0.9, 0.2]	0.08	[-1.0, 0.9]	0.00
Functional regions
Motor	[-0.9, 0.0]	0.08	[-0.8, 0.5]	0.01	[-2.0, 0.4]	0.09
Somatosensory	[-1.0, 0.2]	0.04	[-1.0, 0.4]	0.05	[-1.7, 1.7]	0.00
Spatial	[-1.3, 0.1]	0.06	[-1.8, 0.1]	0.15	[-1.5, 2.4]	0.01
Language	[-0.9, 0.2]	0.05	[-1.0, 0.6]	0.01	[-0.7, 1.7]	0.04
Working Memory	[-0.5, 0.3]	0.01	[-0.6, 0.6]	0.00	[-0.7, 1.3]	0.02
Executive	[-0.7, 0.2]	0.03	[-0.7, 0.6]	0.00	[-0.7, 1.1]	0.02
Emotion	[-0.9, 0.2]	0.05	[-1.1, 0.5]	0.03	[-0.5, 1.8]	0.07