Table 5. Relationships of length of sobriety (LOS, years) to cerebellar volume for AL men and women.

The 95% confidence interval (CI) of the slope (B) for volumes (as a proportion of estimated total intracranial volume, expressed as a percentage of the overall means) and partial r² as a function of LOS are presented for all alcoholics combined, as well as AL men and women separately. Partial r² was calculated with the formula: SS_term/(SS_term + SS_error). Age was included as a covariate for all analyses. No significant group by gender interactions were identified. Effects significant at p < 0.05 are in bold.

	Length of Sobriety (years)
	All AL		AL Men		AL Women
	N=44		N=23		N=21
Structural regions	95% CI	Partial r2	95% CI	Partial r2	95% CI	Partial r2
Total Cerebellum	[-0.2, 0.4]	0.02	[-1.7, 0.7]	0.03	[-0.6, 0.2]	0.07
White Matter	[-0.4, 0.4]	0.00	[-2.6, 1.0]	0.04	[-0.7, 0.5]	0.01
Gray Matter	[-0.2, 0.5]	0.02	[-1.7, 1.0]	0.02	[-0.6, 0.2]	0.06
Anterior Lobe	[-0.3, 1.0]	0.02	[-2.2, 4.3]	0.02	[-1.3, 0.6]	0.04
Posterior Lobe	[-0.2, 0.5]	0.01	[-2.1, 0.9]	0.04	[-0.7, 0.2]	0.05
Vestibulocerebellum	[0.0, 1.2]	0.10	[-1.2, 4.5]	0.07	[-0.5, 1.1]	0.03
Cerebrocerebellum	[-0.2, 0.5]	0.02	[-1.5, 1.2]	0.00	[-0.7, 0.3]	0.04
Spinocerebellum	[-0.2, 0.6]	0.03	[-2.4, 1.0]	0.03	[-0.7, 0.3]	0.05
Functional regions
Motor	[-0.2, 0.7]	0.04	[-2.4, 1.7]	0.01	[-0.6, 0.7]	0.00
Somatosensory	[-0.4, 0.7]	0.00	[-1.8, 2.5]	0.00	[-1.1, 0.7]	0.02
Spatial	[-0.7, 0.6]	0.00	[-3.9, 2.1]	0.02	[-1.5, 0.6]	0.05
Language	[-0.3, 0.7]	0.02	[-3.1, 1.5]	0.03	[-0.9, 0.3]	0.05
Working Memory	[-0.4, 0.3]	0.00	[-2.9, 0.7]	0.08	[-0.8, 0.2]	0.08
Executive	[-0.2, 0.6]	0.02	[-2.8, 1.1]	0.04	[-0.7, 0.2]	0.05
Emotion	[-0.3, 0.7]	0.01	[-3.3, 1.6]	0.03	[-1.0, 0.3]	ss0.06