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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Nanomedicine. 2016 Mar 3;12(5):1231–1239. doi: 10.1016/j.nano.2016.01.003

Figure 5.

Figure 5

Sterically stabilizedliposome- encapsulated IPA-3 induces apoptosis in PC-3 cell tumor xenografts in athymic nude mice. (A)Pictures of PC-3 cell tumor xenograft sections from athymic nude mice treated with vehicle (DMSO), empty liposomes, IPA-3or liposome encapsulated IPA-3 on day 25 after tumor implantation and day 18 after the start of treatments stained with apoptotic marker TUNEL. (B) Histogram showing number of apoptotic (TUNEL positive) cells inPC-3 cell tumor xenograft sections from athymic nude mice treated with vehicle (DMSO), empty liposomes, IPA-3or liposome encapsulated IPA-3 on day 25 after tumor implantation and day 18 after the start of treatments. (n = 4). Data are presented as the mean ± SEM; *p < 0.05; #p < 0.01.