Table 1.
Baseline (1987–89) Participants Characteristic Stratified by Incident Myocardial Infarction during follow up (1996–1998).
| Mean± SD or n (%) | No MI (n=8,795) | SMI (n=317) | CMI (n=386) | p-value* | p-value† |
|---|---|---|---|---|---|
| Age (years) | 54 ±5.6 | 55 ±5.9 | 55 ±5.6 | 0.289 | <.001 |
| Women | 5154 (59) | 139 (44) | 107 (28) | <.001 | <.001 |
| African-American | 1802 (20) | 74 (23) | 54 (14) | 0.001 | 0.003 |
| Education ≤ high school | 4483 (51) | 161 (51) | 227 (59) | 0.033 | 0.011 |
| Current smoker | 1814 (21) | 80 (25) | 120 (31) | 0.004 | <.001 |
| Body mass index (kg/m2) | 27 ±5.0 | 29 ±5.7 | 28 ±4.3 | 0.063 | <.001 |
| Systolic blood pressure (mmHg) | 118 ±17 | 125 ±19 | 125 ±19 | 0.783 | <.001 |
| Hypertension | 2347 (27) | 128 (41) | 152 (39) | 0.783 | <.001 |
| Antihypertensive medication | 1966 (22) | 109 (34) | 116 (30) | 0.221 | <.001 |
| Diabetes | 644 (7.4) | 53 (17) | 64 (17) | 0.970 | <.001 |
| Ratio of total /HDL cholesterol | 4.4 ±1.6 | 4.8 ±1.7 | 5.7 ±1.6 | <.001 | <.001 |
| Cholesterol lowering medication | 202 (2.3) | 7 (2.2) | 12 (3.1) | 0.463 | 0.578 |
| Aspirin use | 4016 (46) | 144 (46) | 166 (43) | 0.531 | 0.579 |
| Family history of coronary heart disease | 3462 (39) | 138 (44) | 199 (52) | 0.034 | <.001 |
| Serum creatinine (mg/dL) | 1.1 ±0.3 | 1.1 ±0.2 | 1.2 ±0.2 | 0.130 | <.001 |
*
p-value for comparison between silent and clinical MI using unpaired student T test and Chi2 for continuous and categorical variables, respectively
†
p-value for comparison among the three groups using analysis of variance and Chi2 for continuous and categorical variables, respectively.