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. Author manuscript; available in PMC: 2016 Jun 2.
Published in final edited form as: Cell Rep. 2016 May 19;15(9):1986–1999. doi: 10.1016/j.celrep.2016.04.078

Figure 1. HIV trimers and their particulate display.

Figure 1

(A) Negative stain EM micrographs of JRFL gp140-foldon oligomers, JRFL NFL2P, and JRFL SOSIP trimers. Scale bars = 20nm. (B) Schematic representation of liposomes displaying HIV-1 trimers. Zoomed field depicts binding of the 6-histidine repeats (His6 tag) present as a fusion on the C-terminus of each protomer of each trimer to the Ni+2 chelated at the hydrophilic head group of the DGS-NTA(Ni) polar lipid.