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. Author manuscript; available in PMC: 2016 Jun 2.
Published in final edited form as: Cell Rep. 2016 May 19;15(9):2025–2037. doi: 10.1016/j.celrep.2016.04.018

Figure 5. SLNCR1 mediated invasion requires AR and Brn3a.

Figure 5

(A and D) MMP9 activity of A375 cells transfected with the indicated plasmids and siRNAs, as in Figure 3 (C–E). (B and E) Relative luciferase activity of A375 cells transfected with an MMP9-RL reporter, as well as the indicated plasmids and siRNAs. Quantification was performed as in Figure 3G. (C and F) Matrigel invasion assay of A375 melanoma cells transfected with the indicated plasmids and siRNAs. The top panel shows representative images of the indicated invading or mobile cells, and the quantification from 3 independent replicates is shown at the bottom. Significance was calculated using the Student’s t-test: * p-value < 0.05, n.s. = not significant. See also Figure S5.