Table 1.
Grade of steatohepatitis | Staging Fibrosis | |||||
---|---|---|---|---|---|---|
Grade | Steatosis | Ballooning | Lobular Inflam. | Portal Inflam. | Stage | Fibrosis |
Mild | Involves up to 2/3rds | Occasional, zone 3 | Scattered, mild acute and chronic | None or mild | 0 | None |
Moderate | Any degree | Obvious, zone 3 | Mild, associated with ballooning | Mild to moderate | 1 | Zone 3 perisinusoidal fibrosis only |
Severe | Typically more than 2/3rds | Marked, mainly zone 3 | Mild to moderate | Mild to moderate | 2 | Zone 3 perisinusoidal fibrosis and periportal fibrosis |
3 | Bridging fibrosis | |||||
4 | Cirrhosis |