FIGURE 7.

The effect of dexa treatment on MoDC levels of endocytosis. The ability of immature/iMoDC (untreated), mature/mMoDC (maturation cocktail treated) to endocytose APC^∗-labeled OVA was assessed. Cells were incubated with OVA at 4°C as a negative control (blue dots), or at 37°C (red dots), for 1 h before flow cytometric analysis of APC^∗ fluorescence. Each dot represents the percentage of cells fluorescing APC^∗, indicating endocytic OVA uptake, in individual experiments. Lines represent mean percentages of cells associated with OVA-APC^∗ ±SEM. One-way ANOVA was used to assess significance followed by Bonferroni’s multiple comparison test, ^∗p < 0.05.